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  Health Information Center  :  D  :  Dipyridamole

 Dipyridamole

 


Common brand name: Persantine

Why is this drug prescribed?
Dipyridamole is used with other medicines to prevent blood clots and problems such as stroke.

How and when should dipyridamole be used?
Dipyridamole comes in tablets and is usually taken three or four times a day. Swallow tablets whole with a full glass of water, coffee, tea, milk, or juice. Your prescription label tells you how much to take at each dose. Follow these instructions carefully and ask your doctor or pharmacist to explain any part you do not understand. Dipyridamole must be taken regularly to be effective. A clinical response might require two to three months of continuous therapy, so follow the schedule prescribed by your doctor. Continue to take dipyridamole even if you feel well. NEVER stop taking dipyridamole without talking to your doctor.

Ask your pharmacist any questions you have about refilling your prescription.

What special instructions should I follow while using this drug?
Before taking this medicine, tell your doctor:

  • If you are allergic to dipyridamole or any other drugs
  • What vitamins, herbals, dietary supplements, and other prescription and non-prescription (over-the-counter) drugs you are taking.
  • If you have or have ever had low blood pressure.
  • If you are pregnant, are trying to become pregnant, become pregnant while taking this medicine, or are breastfeeding

Your doctor might give you other instructions, as well.

  • If your doctor told you to take aspirin with this medicine, take ONLY the amount of aspirin prescribed.
  • Take medicine one hour before or two hours after meals.
  • Tell your doctor or dentist if you are taking dipyridamole if you are having surgery, including dental surgery.
  • Watch for signs of abnormal bleeding if you are taking persantine for long-term therapy. Report any signs or symptoms to your doctor.
  • Keep all appointments with your doctor so your response to the drug can be monitored.
  • Be sure you always have enough of this medicine. Check your supply before vacations and other occasions.

What should I do if I forget to take a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What are the common side effects? What can I do about them?
Although side effects from dipyridamole are not common, they can occur. Some side effects include:

  • Headache
  • Dizziness
    Stand up slowly from a sitting or lying position to decrease dizziness.
  • Flushing, weakness, or fainting
    Contact your doctor if these symptoms are persistent or severe.
  • Nausea, vomiting, or upset stomach
    Eat a light snack when you take the medication.
  • Skin rash
    Contact your doctor.

When should I call my doctor?
Call your doctor right away if you:

  • Develop a skin rash
  • Experience any unusual bleeding or bruising, chest pain, or yellowing of the skin or eyes
  • Experience persistent or severe side effects
  • Have a fever of 101°F (38.3°C) or higher
  • Have any other symptoms that cause concern

What storage conditions are necessary for this drug?

  • Keep dipyridamole in the container it came in, tightly closed.
  • Store tablets at room temperature and away from heat and moisture (not in bathroom).
  • Keep dipyridamole out of the reach of children.
  • Never share your medicine with anyone.
  • Never take outdated medicine. Some prescription labels list an expiration date. If such a date is not on your medicine label or if you are unsure how old a drug is, call your pharmacy.

This handout summarizes information to help you understand and safely take your medicine. Other information--not included in this handout--might be important for you to know because of your unique health status. Ask your doctor and/or pharmacist for more information on the medicines prescribed for you and your unique health care needs.   








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