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  Health Information Center  :  C  :  Colorectal Cancer

 Colorectal Cancer Glossary

 


Abdominoperineal resection
The surgical removal of the anus, rectum and sigmoid colon, resulting in the need for a permanent colostomy

Abscess
A localized formation of pus in a cavity caused by the disintegration or displacement of tissue due to bacterial infection

Acetaminophen
A drug that reduces pain and fever (but not inflammation)

Acute
Abrupt onset that usually is severe; happens for a limited period of time

Adenoma
Benign (non-cancerous) polyps that are considered precursors, or the first step toward colon and rectal cancer

Adhesion
A band of scar tissue that connects two surfaces of the body that normally are separate

Adjuvant therapy
Treatment provided in addition to the primary treatment to prevent cancer recurrence

Adverse effect
A negative or harmful effect

Analgesic
Medicine with pain-relieving qualities

Anemia
A condition called a low red blood cell count. It may occurs when there is not enough hemoglobin or vitamin B12 in a person’s blood. Hemoglobin is a substance in the red blood cells that enables the blood to transport oxygen through the body.

Antibiotic
Medication used to treat bacterial infection

Antibodies
Proteins produced by the body to protect itself from foreign substances (such as bacteria or viruses)

Antigens
Substances that cause an immune response in the body. The body produces antibodies to fight antigens, or harmful substances, and try to eliminate them.

Anti-inflammatory
Medication used to reduce pain, swelling or other irritation

Air contrast barium enema
Also called double contrast barium enema -- an X-ray examination of the entire large intestine (colon) and rectum in which barium and air are introduced gradually into the colon by a rectal tube. This test is recommended along with flexible sigmoidoscopy every five years, starting at age 50, to screen for colorectal cancer and polyps.

Anal fissure
A split or crack in the lining of the anal opening, usually caused by the passage of very hard or watery stools

Anastomosis
A surgical joining of two ducts, blood vessels or bowel segments to allow flow from one to the other

Aneurysm
The abnormal enlargement or bulging of a blood vessel, caused by damage or weakness in the blood vessel wall

Angiogram
A technique that uses dye to highlight blood vessels

Anoscopy

The examination of the anus with a short, metal scope. The anoscopy procedure is used to look for hemorrhoids, anal polyps or other causes of bright-red rectal bleeding.

Anus
The opening of the rectum positioned in the fold between the buttocks, situated at one end of the digestive tract where waste is expelled

APC
A type of gene that normally works by producing a protein to help slow down the rate at which cells divide and grow (APC is a "tumor suppressor gene.")

Asymptomatic
No symptoms; no clear sign that disease is present

Banding
A technique where chromosomes are stained with fluorescent or chemical dyes to determine their characteristics

Barium
A substance that, when swallowed or given rectally as an enema, makes the digestive tract visible on X-rays (also referred to as a "contrast medium")

Barium enema
A way of examining the colon in which barium is given as an enema (through the rectum). Usually gas is then blown in to make the barium spread over the lining of the colon, producing an outline of the colon on X-ray to reveal any irregularities in the lining, such as a polyp.

Benign tumor
A non-cancerous growth that does not spread to nearby tissues or other parts of the body

Biofeedback
A method of learning to modify a particular bodily function by monitoring it with the aid of an electronic device that may produce sight or sound signals. Pelvic floor biofeedback may be recommended for some patients who have an underlying pelvic floor neuromuscular dysfunction.

Biological therapy
See immunotherapy

Biopsy
The removal and examination of a sample of tissue with a microscope to see whether cancer cells are present

Brachytherapy
The treatment of cancer with a radiation source that is applied in or near the tumor

Cancer
A general term for more than 100 diseases in which there is an uncontrolled, abnormal growth of cells. Cancer cells can spread through the bloodstream and lymphatic system to other parts of the body.

Cannulas
Tubes that hold the laparoscope and instruments, and allow access to the abdominal cavity for performance of laparoscopic surgery

Carcinoma
Malignant (cancerous) growth that begins in the lining or covering of an organ and tends to invade surrounding tissue and metastasize (travel to and grow in) to other regions of the body. The tumor is firm, irregular and nodular with a well-defined border.

Carcinoma in situ
Cancer that involves only the tissue in which it began; it has not spread to other tissues

Catheter
A thin, flexible, plastic tube. A urinary catheter is a tube that is inserted into the bladder to drain urine.

CAT scan
Computerized axial tomography, an X-ray technique that produces a film showing a detailed cross-section of tissue

Chemotherapy
Treatment with anticancer drugs. In cancer treatment, chemotherapy refers to the use of drugs whose main effect is either to kill or slow the growth of rapidly multiplying cells. Chemotherapy usually includes a combination of drugs, since this is more effective than a single drug given alone. There are many drug combinations used to treat prostate cancer.

Chronic
Persisting over a long period of time

Clear margins
An area of normal tissue that surrounds cancerous tissue, as seen during a microscopic examination

Clinical trial
A research program conducted with patients to evaluate a new medical treatment, drug or device

Colectomy, partial
A surgical procedure that involves removing part of the colon with anastomosis (or a joining) of the ends that remain. This is used to treat cancer of the colon or severe, chronic ulcerative colitis.

Colectomy, segmental
A surgical procedure that involves removing segments of the colon. This is used to treat cancer of the colon or severe, chronic ulcerative colitis.

Colectomy, total
A surgical procedure that involves removing the entire colon, with the small intestine being attached to the rectum. This is used to treat cancer of the colon or severe, chronic ulcerative colitis.

Colitis
See ulcerative colitis.

Colon
The last six feet of the intestine (except for the last eight inches, which is called the rectum); synonymous with the "large intestine" or "large bowel"

Colon cancer
A malignant (cancerous) tumor arising from the inner wall of the large intestine. Although the exact causes of colon cancer are not known, it appears that both hereditary and environmental factors play a role in its development. The early stages of cancer may have no symptoms. Therefore, regular screening is important.

Colon and rectal surgeon
Experts in the surgical and non-surgical treatment of colon and rectal problems. Colon and rectal surgeons treat benign and malignant conditions, perform routine screening examinations and surgically treat problems when necessary. They have completed advanced training in the treatment of colon and rectal problems in addition to full training in general surgery.

Colonoscopy
An outpatient procedure in which a physician inserts a colonoscope (a long, flexible instrument about Ѕ inch in diameter) in the rectum and advances it to the large intestine (colon) to view the rectum and entire colon

Colostomy
The surgical creation of an opening between the surface of the skin and the colon; also referred to as a large intestine stoma

Computed axial tomography (CAT scan or CT scan)
A technique in which multiple X-rays of the body are taken from different angles in a very short period of time. These images are collected by a computer to give a series of cross-sectional "slices" of the body. Contrast material. such as barium. can be given to distinguish the bowel from the muscle, or the bladder from the rectum.

Constipation
Difficult, infrequent or incomplete passage of stools. Constipation usually is caused by inadequate fiber in the diet or a disruption of regular routine or diet. Constipation can also be caused by overuse of laxatives. Constipation is rarely the sign of a more serious medical condition.

Contraindication
A factor that makes use of a drug or other treatment inadvisable

Corticosteroids
Anti-inflammatory drugs (for example, prednisone) used to treat gastrointestinal disorders such as Crohn's disease or ulcerative colitis. These powerful drugs often produce dramatic results but also cause severe side effects when used over a long period.

Crohn's disease
A chronic inflammatory disease that involves all layers of the intestinal wall. It primarily affects the lower part of the small intestine, called the ileum, but it can affect any part of the large or small intestine, stomach or esophagus. Crohn's disease can disrupt the normal function of the bowel in a number of ways.

Desmoid tumors
Growths of scar tissue that are very tough and firm. Desmoid tumors are rare among the general public, but are found in 12 percent of patients with familial adenomatous polyposis or FAP.

Diaphragm
Thin, dome-shaped muscle that separates the abdomen from the chest. When the muscle contracts, the dome flattens, increasing the volume of the chest.

Diarrhea
A condition in which bowel movements are passed more often than usual and in a liquid state

Digestive diseases
Disorders that cause the malfunctioning of the digestive system, so that it is no longer turning food into fuel for energy, maintaining the body structure or eliminating waste products properly. Digestive diseases range from the occasional upset stomach, to the more life-threatening colon cancer, and encompass disorders of the gastrointestinal tract, liver, gall bladder and pancreas.

Digital rectal exam (DRE)
When the doctor inserts a gloved finger into the rectum. Some tumors of the rectum and prostate gland can be felt during a DRE.

Diverticulitis
An inflammation or infection of small sacs or outpouchings (diverticula) of the inner lining of the intestine that protrude through the intestinal wall

Diverticulosis
Presence of small sacs or outpouchings (diverticula) of the inner lining of the intestine that protrude through the intestinal wall. These sacs form in weakened areas of the bowel.

DNA (Deoxyribonucleic acid)
The material that controls the genetics and hereditary pertaining to each cell

Double contrast barium enema
See air contrast barium enema.

Duodenum
The first part of the small intestine, connecting with the lower opening of the stomach and extending to the jejunum

Endoscopy
A method of physical examination using a lighted, flexible instrument that allows a physician to see the inside of the digestive tract. The endoscope can be passed through the mouth or through the anus, depending on which part of the digestive tract is being examined. This method is referred to by different names depending on the area of examination, such as: esophagoscopy (esophagus), astroscopy (stomach), upper endoscopy (small intestine), sigmoidoscopy (lower part of the large intestine), and colonoscopy (entire large intestine).

Endosonography
Also called rectal ultrasound, is a diagnostic tool used to visualize the anal sphincter muscles to diagnose the source of bowel incontinence and to evaluate abnormal or cancerous growths. High-frequency sound waves are used to produce images and precisely identify abnormalities. Ultrasound can be used to locate the exact position of the tear in a muscle, even before bowel incontinence becomes a problem.

Enema
Injection of fluid into the rectum and colon to induce a bowel movement

Epidural catheter
A small tube (catheter) passed into the space between the spinal cord and spinal column. Pain medication is then delivered through the tube, numbing the lower abdominal area.

Erythrocytes
Red blood cells that carry oxygen from the lungs to cells in all parts of the body. Erythrocytes also carry carbon dioxide from the cells back to the lungs.

Esophagogastroduodenoscopy (EGD)
An examination of the esophagus, stomach, and duodenum using a thin flexible tube that is placed down the throat. Before the EGD procedure, an anesthetic spray is used to numb the back of the throat, and sedation is given for the 15-minute exam.

Familial adenomatous polyposis (FAP)
A syndrome in which a gene mutation that influences the development of colon, rectal, and other cancers is inherited in a dominant pattern. Dominant inheritance means that only one mutated copy of the gene needs to be received for the disease to be passed on. FAP patients usually have hundreds, and sometimes thousands of pre-cancerous polyps developing at a very early age. FAP is defined as the presence of more than 100 benign (adenomatous) polyps in the large intestine at one examination. Some FAP patients with a mild version of the disease have less than 100 adenomas; in these patients the diagnosis is made by family history, or by finding the mutation during genetic testing.

Fecal diversion
Surgical creation of an opening of part of the colon (colostomy) or small intestine (ileostomy) to the surface of the skin. The opening provides a passageway for stool to exit the body.

Fecal incontinence
Inability to retain stool, resulting in bowel accidents

Fecal occult blood test (FOBT)
Stool testing for blood, which is recommended every year starting at age 50, in addition to the flexible sigmoidoscopy test every five years, to screen for colon cancer and polyps

Fistula
An abnormal connection that forms between two internal organs or between two different parts of the intestine. This is a common complication of Crohn's disease.

Flexible sigmoidoscopy
A routine outpatient procedure in which the inside of the lower large intestine (called the sigmoid colon) is examined. Flexible sigmoidoscopies are commonly used to evaluate bowel disorders, rectal bleeding, or polyps (usually benign growths), and to screen people over age 50 for colon and rectal cancer. During the procedure, a physician uses a sigmoidoscope (a long, flexible instrument about 1/2 inch in diameter) to view the lining of the rectum and the large intestine. The sigmoidoscope is inserted through the rectum and advanced into the large intestine (colon) to view the lining of the rectum and the lower third of the large intestine (sigmoid colon).

Fluoroscopy
A continuous X-ray technique that allows the physician to observe how an organ performs its normal function; for example, how the esophagus works during swallowing.

Gas
A product of digestion that is made primarily of odorless vapors — carbon dioxide, oxygen, nitrogen, hydrogen and sometimes methane. The unpleasant odor is due to bacteria in the large intestine that release small amounts of gases containing sulfur. Everyone has gas and eliminates it by burping or passing it through the rectum. In many instances people think they have too much gas, when in reality they have normal amounts. Most people produce one to three pints of intestinal gas in 24 hours, and pass gas an average of 14 times a day.

Gastroenterologist
Experts in the treatment of diseases of the digestive (gastrointestinal) tract. They have completed advanced training in the treatment of digestive problems.

Gene
The basic unit of heredity found in all cells. Each gene occupies a certain location on a chromosome (a linear thread in the nucleus of a cell that contains the DNA that transfers genetic information). Genes are self-producing, minuscule structures capable under certain circumstances of giving rise to a new character, also known as a mutation. Hereditary traits are controlled by pairs of genes in the same position on a pair of chromosomes.

Genetic counseling
A process in which a genetic counselor obtains a complete family and personal medical history in order to determine the probable existence of a genetic problem occurring within a family. The interpretation and implications of genetic testing are discussed. Often used for prospective parents in order to provide information about risks of diseases prior to conception, or during pregnancy. A genetic work-up also helps inform those who are at risk of inheriting hereditary non-polyposis colorectal cancer (HNPCC) and familial adenomatous polyposis (FAP).

Genetic testing
Blood or tissue tests that may be ordered to detect the presence of genetic abnormalities that predispose a person to certain diseases, such as cancer. For patients and families suspected of having an inherited disease it may be possible to find the mutation causing the disease through genetic testing of blood. Genetic counseling should be done by experts before genetic tests are performed.

Grade
A labeling system indicating how aggressive a cancer is

Hemorrhoids
Swollen blood vessels which line the anal opening, caused by excess pressure from the straining during a bowel movement, persistent diarrhea or pregnancy

Hepatitis
A disease in which the liver is inflamed. A viral infection is usually the cause of hepatitis, although sometimes toxins or drugs are the cause.

Hereditary non-polyposis colorectal cancer (HNPCC)
HNPCC is a syndrome in which a gene mutation that influences the development of colon, rectal and other cancers is inherited in a dominant pattern. Dominant inheritance means that only one mutated copy of the gene needs to be received for the disease to be transferred to the next generation. Colon and rectal cancer occurs frequently in HNPCC families, whose lifetime risk of the disease is up to 70 percent. HNPCC causes cancer to occur more frequently in the uterus, ovary, stomach, small bowel, kidney and bladder.

Hormonal therapy
The use of hormones to treat cancer patients by removing, blocking or adding to the effects of a hormone on an organ or part of the body

Hormones
Chemicals produced by glands in the body. Hormones control the actions of certain cells or organs

Ileal (J) Pouch
A pouch is used to replace the rectum after a total proctocolectomy as a reservoir for stool.There are four forms of the ileal pouch, named after the shape in which the end of the small intestine (the ileum) is placed before it is sewn (or stapled) to make a pouch. The most common form is the "J" pouch, but there also are the "S," the "H" and the "W" pouches. The pouch is sewn or stapled to the anus. Pouch surgery is complex and has a relatively high risk of complications. Because of this a temporary ileostomy usually is needed, with it being closed three months after the pouch has healed.

Ileocolectomy
Surgical removal of a section of the terminal ileum and colon lying close to the ileum (the lowermost part of the small intestine)

Ileorectal anastomosis
The surgical connection of the ileum and the rectum

Ileostomy
The surgical creation of an opening between the surface of the skin and the ileum, the lowermost section of the small intestine

Ileum
The lower three fifths of the small intestine from the jejunum to the ileocecal valve

Immune system
The body’s natural defense system against infection or disease

Immunotherapy
Treatment to stimulate or restore the ability of the immune system to fight infection and disease; also called biological therapy

Incontinence (bowel)
Loss of bowel control

Inflammation
One of the body’s defense mechanisms, inflammation results in increased blood flow in response to infection and certain chronic conditions. Symptoms of inflammation include redness, swelling, pain and heat.

Inflammatory bowel disease (IBD)
Diseases that cause inflammation of the bowel. IBD includes Crohn's disease and ulcerative colitis.

IV
See intravenous.

Intravenous
Within a vein or veins; medications may be given intravenously through a small tube, IV (or catheter)

Irritable bowel syndrome (IBS, also called spastic colon)
A condition in which the colon muscle contracts more readily and causes abdominal pain and cramps, excess gas, bloating and a change in bowel habits that alternate between diarrhea and constipation

Jejunum
The second portion of the small intestine extending from the duodenum to the ileum

Laparoscopy or laparoscopic surgery
A method of surgery that is much less invasive than traditional surgery. Tiny incisions are made to create a passageway for a special instrument called a laparoscope. This thin telescopelike instrument with a miniature video camera and light source is used to transmit images to a video monitor. The surgeon watches the video screen while performing the procedure with small instruments that pass through small tubes placed in the incisions.

Large intestine
The digestive organ made up of the ascending (right) colon, the transverse (across) colon, the descending (left) colon and the sigmoid (end) colon. The appendix is also part of the large intestine. The large intestine receives the liquid contents from the small intestine and absorbs the water and electrolytes from this liquid to form feces, or waste.

Laser surgery
Destruction of tissue using a small, powerful, highly focused beam of light

Laxative
Medications that increase the action of the intestines or stimulate the addition of water to the stool to increase its bulk and ease its passage. Laxatives often are prescribed to treat constipation.

Leukocytes
White blood cells that protect the body against infections and other diseases

Leukopenia
A decreased white blood cell count

Local therapy
Treatment that affects cells in the tumor and the area close to it

Localized cancer
Cancer that hasn’t spread to other parts of the body

Lymph
Clear fluid that travels through the lymphatic system and carries cells that help fight infection and disease

Lymphatic system
A circulatory system that includes an extensive network of lymph vessels and lymph nodes. The lymphatic system helps coordinate the immune system’s function to protect the body from foreign substances.

Magnetic resonance imaging (MRI)
A test that produces images of the body without the use of X-rays. MRI uses a large magnet, radio waves and a computer to produce these images.

Malignant
Cancerous; can spread to other parts of the body

Mesentery
Membranous tissue that carries blood vessels and lymph glands, and attaches various organs to the abdominal wall

Metastasize
To spread from one part of the body to another. When cancer cells metastasize and cause secondary tumors, the cells in the secondary tumor are like those in the original cancer.

Microsatellite instability
The mistakes in DNA. Microsatellite instability is where the length of small sequences of DNA differ between tumor cells and normal cells; their appearance is a clue to the presence of abnormal DNA repair.

Mismatch repair genes
The genes responsible for correcting errors in DNA when cells divide. In hereditary non-polyposis colorectal cancer (HNPCC), recent research has discovered mutations in a variety of genes that are thought to be a part of the DNA mismatch repair system, therefore predisposing families with HNPCC to the development of cancer. The two most commonly mutated genes, known as hMLH1 and hMSH2, could account for up to 50% of HNPCC cases.

Mismatch repair
The process that takes place in the cells of almost every living organism. DNA mismatch repair is when DNA replicates in the nucleus of a cell by DNA exonuclease enzymes separating the two strands of the double helix, making each a template upon which a new double helix is built. DNA polymerase then adds new nitrogenous bases to each strand: adenine binds to thymine; guanine binds to cytosine. At the completion of the replication, one DNA double helix has become two double helices. If a mistake or mismatch occurs, there is a set of at least 6 genes that produce proteins whose job is to recognize a mistake or mismatch, cut it out, and replace it with the correct sequence of DNA. If one of these genes is mutated (or changed) and doesn't make a protein that works, the whole system fails.

Muscle transposition
A procedure in which gluteal (buttock) or gracilis (inner thigh) muscles are used to encircle and strengthen the anal canal. When the inner thigh muscle is used, pacemaker-like electrodes are implanted into the grafted muscle to train it to remain contracted. When the buttock muscle is used, the lower portion of this muscle is freed from the tailbone region and wrapped around the anus to construct a new anus. The buttock muscle transposition does not require the use of a pacemaker.

Mutation
A change in a gene with the potential of being transmitted to offspring

Nausea
A queasy feeling that leads to stomach distress, a distaste for food and an urge to vomit. Nausea is not a disease, but a symptom of many disorders. It can be brought on by systemic illnesses such as influenza, medications, pain and inner ear disease.

Nitrates
Substances found in some foods, especially meats, prepared by drying, smoking, salting or pickling. Nitrates are thought to be cancer-causing substances that contribute to the development of certain types of cancer.

Non-steroidal anti-inflammatory drugs (NSAIDs)
A class of drugs that is effective in reducing inflammation and pain without steroids. Examples of these drugs include aspirin, naproxen and ibuprofen.

Occult blood
Blood in the stool that is not visible to the naked eye. This type of bleeding is detected by performing a laboratory test on a stool sample.

Oncologist, medical
A physician who specializes in the medical treatment of cancer. Medical oncologists have a thorough knowledge of how cancers behave and grow. This knowledge is used to calculate your risk of recurrence as well as the possible need for and benefits of additional or adjuvant therapy (such as chemotherapy, hormonal therapy or bone marrow transplantation). Your medical oncologist generally manages your overall medical care and monitors your general health during your course of treatment. He or she checks your progress frequently, reviews your lab and X-ray results and coordinates your medical care before and after your course of treatment.

Oncologist, radiation
A physician trained in cancer treatment using radiation therapy

Oncologist, surgical
A doctor who performs biopsies and other surgical procedures to diagnose and treat cancer

Ostomy
A general term meaning an opening, especially one made by surgery; see also colostomy

Pathology
The study of the characteristics, causes and effects of a disease

Pathologist
An expert who specializes in analyzing tissue samples (removed during a biopsy) under a microscope to detect the cellular makeup of the tumor, whether the cancer is localized or has the potential to spread and how quickly it is growing. Pathologists can detect subtle differences in cancer cells that help your surgeon and oncologist confirm the diagnosis.

PCA
Abbreviation for Patient Controlled Analgesia, a method of administering pain medication directly into a patient's circulatory system through a vein (usually in the arm or hand) or directly to the nerves that perceive lower abdominal pain (epidural area). Delivery of pain medicine is activated by the patient pushing a request button.

Peristalsis
The means by which food or waste is propelled through the gastrointestinal tract in a series of muscular contractions.

Platelets
Substance in blood that helps prevent bleeding by causing blood clots to form at the site of an injury

Polyps (colon)
Small growths on the inner colon lining. Certain types of polyps, such as adenomas, may develop into cancer. Other types of polyps, such as hyperplastic polyps, have no risk of developing into cancer. Colorectal screening is important to detect polyps and early cancer.

Proctocolectomy
The surgical removal of the entire colon that may be performed in one or more stages. Proctocolectomy cures colon cancer and removes all risk of developing the disease in the colon or rectum.

Proctoscopy
A procedure in which a 10-inch straight metal scope is used to examine the rectum. The patient is normally on his or her side for this exam, and a fleet enema is usually given before the procedure.

Proctosigmoidectomy
An operation that removes a diseased section of the rectum and sigmoid colon

Prognosis
The probable outcome or course of a disease; the chance of recovery

Pulse oximetry
A photoelectric device that measures the percent of oxygenation in the blood using a clip on the finger; also measures the heart rate.

Radiation
A form of cancer treatment that uses high levels of radiation to kill cancer cells or keep them from growing and dividing — while minimizing damage to healthy cells

Radiation, internal
When small amounts of radioactive materials are introduced into the body to help prevent, diagnose and treat disease. Brachytherapy is the treatment of cancer with a radiation source that is applied in or near the tumor.

Radiation, external
The use of radiation delivered by special equipment that directs the radiation from outside the body through normal tissue to reach the cancer. This type of radiation to treat cancer often is given in short sessions over a period of time.

Radiation oncologist
A doctor who specializes in using radiation to treat cancer

Radiation therapist
A professional who helps place you in the correct treatment position and interprets X-ray studies

Radiation technologist
A professional who checks the radiation dosage to make it as safe as possible

Radiology
A branch of medicine that uses radioactive substances and visual devices to diagnose and treat a wide variety of diseases

Radiologist
A physician who reads and interprets X-rays and other radiographic images

Rectal bleeding
A symptom of digestive problems rather than a disease. Bleeding can occur as a result of a number of different conditions, many of which are not life-threatening. Most causes of bleeding are related to conditions that can be cured or controlled, such as hemorrhoids. However, rectal bleeding may be an early sign of rectal cancer so it is important to locate the source of the bleeding.

Rectal prolapse
Dropping down of the rectum outside the anus

Rectopexy
Surgical placement of internal sutures (stitches) to secure the rectum in its proper position

Rectum
An 8-inch chamber connected to the large intestine that receives solid waste (feces) from the descending colon to be expelled from the body. The rectum connects the colon to the anus. It is the rectum's job to receive stool from the colon, to let the person know that there is stool to be evacuated and to hold the stool until evacuation happens.

Recurrence
The return of a disease after a period of remission

Remission
Disappearance of the signs and symptoms of cancer. A remission can be temporary or permanent.

Risk factor
A factor that increases a person’s chance of developing a disease or predisposes a person to a certain condition

Sentinal lymph node
The first lymph node to which a tumor drains, making it the first place where cancer is likely to spread

Sigmoidoscopy
See flexible sigmoidoscopy.

Small intestine
The portion of the digestive tract that first receives food from the stomach. It is divided into three sections: the duodenum, the jejunum and the ileum. As food travels through the small intestine it is further broken down by enzymes, and nutrients from the food are absorbed into the bloodstream.

Sphincteroplasty
Also called rectal sphincter repair, is the most common procedure used to correct a defect in the anal sphincter muscles. There are two anal muscles that control bowel movements, similar to two round doughnuts, one inside of the other. If a defect exists in the complete circle of muscle, the problem can be corrected with this surgery. During the sphincteroplasty, the two ends of the muscle are cut and overlapped onto one another, then sewn in place. This procedure then restores the complete circle of muscle.

Stage
The extent of the cancer. The stage of colon cancer depends on the size of the cancer tumor and whether it has spread from its original site to other parts of the body.

Stoma
An artificial opening of the intestine to outside the abdominal wall

Systemic therapy
Treatment that reaches and affects cells all over the body

Thrombosis
A blood clot

Total abdominal colectomy
Surgical removal of the entire colon

Trocar
A sharp, pointed instrument used to make a puncture incision in the abdominal wall; used for placement of cannulas

Tumor
A spontaneous new growth of tissue forming an abnormal mass; also known as a neoplasm

Ulcerative colitis
A disease that causes inflammation and sores, called ulcers, in the top layers of the lining of the large intestine. The inflammation usually occurs in the rectum and lower part of the colon, but it may affect the entire colon. Ulcerative colitis rarely affects the small intestine except for the lower section, called the ileum.

Ultrasound
A test used to diagnose a wide range of diseases and conditions in which high-frequency sound waves, inaudible to the human ear, are transmitted through body tissues. The echoes vary according to the tissue density. The echoes are recorded and translated into video or photographic images that are displayed on a monitor.

Vomiting
The forcible expulsion of the contents of the stomach through the mouth which occurs with symptoms of nausea. Vomiting is not a disease but a symptom of many disorders. Vomiting is also a side effect of some forms of chemotherapy.

X-ray
High-energy radiation used in low doses to diagnose diseases and used in high doses to treat cancer








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