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  Health Information Center  :  C  :  Colorectal Cancer

 Colorectal Cancer: An Overview

 


What is colorectal cancer?
Cancer that begins in the colon is called colon cancer, and cancer that begins in the rectum is called rectal cancer. Cancers affecting either of these organs also might be called colorectal cancer.

Colorectal cancer is the second leading cause of cancer and cancer deaths among American men and women. Each year, more than 130,000 new patients are diagnosed with colorectal cancer, and more than 46,000 colon cancer-related deaths occur.

How does colorectal cancer develop?
Colorectal cancer occurs when the cells that line the colon (also called the large intestine or large bowel) or the rectum (lower portion of the colon) become abnormal and grow out of control.

Unfortunately, many colorectal cancers are "silent" tumors until they are advanced and produce symptoms. Fortunately, through regular colorectal cancer screenings, colorectal cancer is preventable, and curable, if detected early.

Who is at risk for colorectal cancer?
Every one of us is at risk for colorectal cancer. The majority of people who develop colorectal cancer have no known risk factors. The average risk for colorectal cancer is one out of 50 or 2 percent of people. Although anyone can get colorectal cancer, it is most common among people over the age of 50. Women have a higher risk for colon cancer, while men are more likely to develop rectal cancer. Risk factors for colorectal cancer include:

  • A personal history of colorectal polyps (benign growths on the inner wall of the colon and rectum) or cancer (highest risk factor)
  • A diet high in fat and low in fiber
  • Family history of polyps or colorectal cancer
  • Family history of familial adenomatous polyposis, a disease in which hundreds of polyps cover the colon
  • Inflammatory bowel disease (Crohn's disease or ulcerative colitis)
  • Smoking

What are the symptoms of colorectal cancer?
Unfortunately, colorectal cancer might strike without symptoms. For this reason, it is very important to have regular colorectal cancer prevention examinations, called screening. One of the signs of colon cancer might be bleeding. Often tumors bleed only small amounts intermittently, and evidence of the blood is found only during chemical testing of the stool. This is called occult bleeding — it is not always visible to the naked eye. When tumors have grown larger, other symptoms might develop. The symptoms of colorectal cancer include the following:

  • Change in bowel habits (constipation or diarrhea)

  • Blood on or in the stool

  • Unexplained anemia

  • Unusual abdominal or gas pains

  • Unexplained weight loss

  • Fatigue

  • Vomiting

How can I protect myself from colorectal cancer?
Living a healthy lifestyle that includes regular exercise; maintenance of a healthy weight; and a diet that is low in fat and high in fiber, vegetables, and fruit is probably your best start to general cancer prevention. Even with recent reports that a high-fiber diet does not necessarily protect against colorectal cancer, eating well and exercising confer so many other health benefits that it would be wise to adopt or maintain those lifestyle changes.

Going to the doctor as recommended so he or she can check the colon for polyps and cancer is the next important step. Screening recommendations depend upon an individual's risk of colorectal cancer. The goal is to identify people at high risk of developing colon cancer and screen them earlier than the general population.

The screening recommendations for people without any symptoms that might suggest colorectal cancer or polyps include:

  • Digital rectal exam performed in men once a year, every year after age 40







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