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  Health Information Center  :  A  :  Anxiety Disorder

 Clorazepate

 


Common brand name: Tranxene

Type of medication: Anticonvulsant, antianxiety

Why is this drug prescribed?
Clorazepate is prescribed to treat epilepsy. It helps control the frequency and severity of seizures by slowing down the central nervous system. It may also be used to treat other conditions such as anxiety or difficulty sleeping.

How is clorazepate given?
Clorazepate comes in the form of a tablet to be taken by mouth with or without food. Individual doses vary, and your doctor will tell you how much to take at each dose. In order for clorazepate to effectively control your seizures, it is important that a constant amount of it remains in the bloodstream. In order to accomplish this, try taking the drug around the same time everyday as ordered by your doctor.

Follow the directions on the prescription label carefully. If there is any part that you do not understand, ask your doctor or pharmacist. Do not take any more or less than prescribed and do not take it more often than prescribed. NEVER stop taking this drug without talking to your physician. This drug will need to be gradually discontinued.

What special precautions should I follow before using this drug?
Before taking clorazepate, inform your doctor of any prescription or over-the-counter medications that you are currently taking; this includes any herbal medications or dietary supplements that you are taking. Also, be sure to tell your doctor if you have any other medical problems including any:

  • Drug or alcohol abuse or a history of
  • Brain diseases
  • Emphysema, asthma, bronchitis or other chronic lung diseases.
  • Glaucoma
  • Hyperactivity
  • Depression
  • Myasthenia gravis
  • Porphyria (inherited diseases characterized by skin sensitivity to sunlight and/or by intermittent acute attacks of abdominal and nerve pain)
  • Sleep apnea
  • Kidney or liver disease

What special instructions should I follow while using this drug?
Clorazepate adds to the effects of other central nervous system suppressants such as alcohol and those found in many antihistamines, cold medications, pain medications and muscle relaxants. Check with your doctor before taking any of these items.

Because this medication can cause drowsiness and dizziness, make sure you are aware of how this drug reacts before driving or using machines that require you to be alert.

Before you have any kind of surgery, dental treatment or emergency treatment, tell your doctor or dentist if you are using this medication.

Your doctor may want you to carry a medical identification card or bracelet stating that you are taking this medication.

What are the common side effects?
The most common side effects of clorazepate include:

  • Clumsiness or unsteadiness
  • Drowsiness
  • Dizziness
  • Slurred speech
  • Skin rash

When should I call my doctor?
If you experience any of the following side effects, contact you doctor immediately:

  • Anxiety
  • Fast, irregular heartbeat
  • Loss of memory of events taking place after the drug has been taken
  • Depression
  • Seizures
  • Difficulty breathing
  • Persistent termor
  • Have any questions or concerns

What should I do if I forget a dose?
If a dose is missed, simply take it as soon as you remember if it is within an hour of the scheduled dose. Otherwise simply skip the missed dose and proceed with your regular schedule. Do not take a double dose.

What storage conditions are necessary for this drug?
Clorazepate should be kept in its original container, tightly sealed and away from children. The tablet form should be stored in room temperature, away from excess heat and moisture (not in the bathroom) and out of direct sunlight. Any medication that is outdated or unused should be thrown away.








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